产品货号:
Z36415
中文名称:
IRS1抗体
英文名称:
Anti-IRS1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-IRS1 Antibody |
指标别名 | HIRS 1;IRS 1;IRS1;IRS-1 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,ICC/IF |
基因名称 | IRS1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human IRS1 |
实际分子量 | 165~180KD |
成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Insulin receptor substrate 1(IRS-1) is a signalling adapter protein that in humans is encoded by the IRS-1 gene.It is mapped to 2q36.3.This gene exhibited no intrinsic enzyme activity,and it can serve as a docking protein involved in binding and activating other signal transduction molecules after being phosphorylated on tyrosine by insulin receptor kinase.IRS1 plays a key role in transmitting signals from the insulin and insulin-like growth factor-1(IGF-1) receptors to intracellular pathways PI3K/Akt and Erk MAP kinase pathways.IRS1 also plays important biological function for both metabolic and mitogenic(growth promoting) pathways.In addition to those,IRS1 is a key regulator of PI3K within malignant cells. |
Uniprot ID | P35568 |
基因名全称 | Insulin receptor substrate 1 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 |
相关搜索:IRS1抗体,IRS1单抗,Anti-IRS1 Antibody